This rare disease not only had a significant impact on her physical health but also on her overall quality of life.Īs an autoimmune disease, scleroderma occurs when the body's immune system mistakenly attacks normal tissues. Gay Saget unfortunately suffered from the systemic form of scleroderma, which is known for its severity and potential complications. Localized scleroderma primarily affects the skin, while systemic scleroderma affects not only the skin but also various organs and tissues, such as the heart, lungs, kidneys, and digestive system. There are two main types of scleroderma: localized and systemic. It is characterized by the overproduction of collagen, a protein that gives structure to the skin and other organs. Scleroderma is an autoimmune disease that causes the hardening and tightening of the skin and connective tissues. What kind of disease did Bob Saget's sister have?
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